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Defne Bayık

 
 DefneBayik      Contact Info: dbayik@bilkent.edu.tr
     Research Interests:
Academic Degrees
2010-….. Ph.D. Molecular Biology and Genetics Bilkent University, Ankara, Turkey Supervisor: Assoc. Prof. İhsan Gürsel
2006-2010 B.S. Molecular Biology and Genetics Bilkent University, Ankara, Turkey
 
Publications
Telkoparan P., Erkek S., Yaman E., Alotaibi H., Bayık D., and Tazebay U.H. Coiled coil domain containing protein 124 is a novel centrosome and midbody protein that is involved in cytokinetic abscission, and it connects cell division to Rap2 signaling. PloS One. 9;8(7):e69289. 2013. (doi: 10.1371/journal.pone.0069289).
 
Research Experiences
2010-… Research assistant TÜBİTAK project (SBAG-111S236). Applications of CpG loaded exosomes in vaccination and cancer therapy. Bilkent University, Department of Molecular Biology and Genetics, Turkey.
 
2009-2010 Senior project Supervisor: Assoc. Prof Uygar H. Tazebay. Identification of a novel coiled-coil domain containing protein. Bilkent University, Department of Molecular Biology and Genetics, Turkey.
 
2009 Summer Internship Supervisor: Dr. Kutluk Oktay, MD. Identification of the effects of Chemotherapy Drugs on Follicle Preservation. and Identification of the changes in the expression of Homeobox Genes regarding to Oocyte.Aging.
Department of Obstetrics & Gynecology, New York Medical College, Valhalla, New York, USA.
 
2008 Summer Internship Supervisor: Dr. Emre Seli, MD. Identification and characterization of mammalian embryonic Poly-A binding protein.
Department of Obstetrics & Gynecology Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut,USA.
 
2007 Summer Internship Supervisor: Dr. B. Ugur Yavuzer, MD. PhD. Identification of the effects of the TATA-box binding proteins on liver cancer.
Faculty of Medicine, Department of Physiology, Akdeniz University, Antalya, Turkey.
 
Scholarships and awards
  • Travel and accomodation awards by EMBO. EMBO Chromosome Structure, Damage & Repair Workshop, Greece, Sept. 2011.
  • Graduate scholarship, TÜBİTAK, 2010-…
  • Full scholarship, Graduate education, Bilkent University, Department of Molecular Biology and Genetics, 2010-…
  • B.S. full scholarship, Higher Education Council, Turkey, 2007-2010.
 
Conference Communications
2013 Bayyurt B., Güçlüler G., Bayık D., Alpdündar E., Yıldız S., Horuluoğlu B.H., Özcan M., Gürsel M. and Gürsel İ. Nano-liposomes co-encapsulating nucleic acid TLR ligands and antigen can be used for long-term cancer vaccine. 22th National Congress of Immunology. Çeşme, Turkey. 27-30 Apr. 2013.
  Güçlüler G., KahramanT., Bayık D., Gürsel A., Gürsel M. and Gürsel İ. Usage of E.G7 exosome loaded with CpG oligonucleotide as vaccine adjuvant and anti-cancer agent. 22th National Congress of Immunology. Çeşme, Turkey. 27-30 Apr. 2013.
  Alpdündar E., Yıldız S., Bayyurt B., Güçlüler G., Bayık D., Özcan M., Güngör B., Gürsel İ. and Gürsel M. Immunomodulatory roles of commensal bacteria-derived membrane vesicles. 22th National Congress of Immunology. Çeşme, Turkey. 27-30 Apr. 2013
  Yıldız S., Alpdündar E., Bayyurt B., Güçlüler G., Bayık D., Özcan M., Güngör B., Gürsel İ. and Gürsel M. Effects of peptide complexes and vesicles encapsulating cyclic-di-GMP as vaccine adjuvant. 22th National Congress of Immunology. Çeşme, Turkey. 27-30 Apr. 2013
  Bayyurt B., Güçlüler G., Bayık D., Alpdündar E., Yıldız S., Horuluoğlu B.H., Özcan M., Gürsel M. and Gürsel İ. Extended anti-cancer immunity by liposomes coencapsulating nucleic acid TLR-ligands and antigen. 15th International Congress of Immunology. Milan, Italy. 22-27 Aug. 2013.
  Güçlüler G., KahramanT., Bayık D., Gürsel A., Gürsel M. and Gürsel İ. D Type CpG oligonucleotide loaded E.G7 exosomes act as strong vaccine adjuvant and anti-cancer agent. 15th International Congress of Immunology. Milan, Italy. 22-27 Aug. 2013.
  Alpdündar E., Yıldız S., Bayyurt B., Özcan M., Güçlüler G., Bayık D., Güngör B., Gürsel İ. and Gürsel M. Commensal bacteria-derived membrane vesicles suppress Th-1 dominated immune responses in vaccinated and tumor-bearing mice. 15th International Congress of Immunology. Milan, Italy. 22-27 Aug. 2013.
  Yıldız S., Alpdündar E., Bayyurt B., Özcan M., Güçlüler G., Bayık D., Güngör B., Gürsel İ. and Gürsel M. Cyclic-di-GMP based immune stimulatory formulations as novel vaccine adjuvants and anti-cancer agents. 15th International Congress of Immunology. Milan, Italy. 22-27 Aug. 2013.
  Güçlüler G., Kahraman T., Bayık D., Horuluoğlu B.H., Gürsel A. and Gürsel İ. CpG ODN Loaded Extracellular Nanovesicles: Enhanced Immunotherapeutic Activity. ILS Liposome Advanced Conference, London, United Kingdom. 13-17 Dec. 2013.
 
2012 Telkoparan P., Erkek S., Alotaibi H., Yaman E., Bayık D., Tazebay U.H. Coiled-coil domain containing protein 124 is a novel centrosome and midbody protein that interacts with the Ras-guanine nucleotide exchange factor 1B and is involved in cytokinesis. 1stInternational Congress of the Molecular Biology Association of Turkey. İstanbul,Turkey, 23-24 Nov. 2012.
 
2011 Bayık, D., Telkoparan, P., Erdoğan, M. and Tazebay U.H. A novel PIKK target coiled-coil-domain containing protein (Ccdc) is associated with double strand-breaks.  EMBO Chromosome Structure, Damage & Repair Workshop. Cape Sounio, Greece. 25-28 Sept. 2011 (Travel and accomodation award)